BDBM50345740 3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1785021::CHEMBL2070048::US10544104, Compound 7r::US11247972, Compound 7r::US9765037, Compound 7r

SMILES CCOc1ccc2cc(ccc2c1)-c1nn(C(C)C)c2ncnc(N)c12

InChI Key InChIKey=MJOCJDMQRCJQJF-UHFFFAOYSA-N

Data  2 KI  25 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345740   

TargetcGMP-dependent protein kinase()
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataIC50:  5nMAssay Description:Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent protein kinase()
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent